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Limitations in the use of indium-111-oxine-labeled leucocytes for the diagnosis of occult infection in children

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Limitations in the use of indium-111-oxine-labeled leucocytes for the diagnosis of occult infection in children

Auteurs : RBID : ISTEX:247_1987_Article_BF02388092.pdf

Abstract

Fifteen children underwent scintigraphy withindium 111 (111In)-labeled white blood cells (WBC) for the detection of a local suppuration. The procedure generally contributed to a correct diagnosis. False negative results were observed in 5 children, but in two of them positive foci were also present. The missed lesions were 2 liver abscesses, 1 lung abscess, foci of osteomyelitis and 1 pericarditis. Two cases of chronic granulomatous disease are presented in which increased leucocyte accumulation was not observed in proven instances of infection.

DOI: 10.1007/BF02388092

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Le document en format XML

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<div type="abstract" xml:lang="eng">Fifteen children underwent scintigraphy withindium 111 (111In)-labeled white blood cells (WBC) for the detection of a local suppuration. The procedure generally contributed to a correct diagnosis. False negative results were observed in 5 children, but in two of them positive foci were also present. The missed lesions were 2 liver abscesses, 1 lung abscess, foci of osteomyelitis and 1 pericarditis. Two cases of chronic granulomatous disease are presented in which increased leucocyte accumulation was not observed in proven instances of infection.</div>
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<abstract lang="eng">Fifteen children underwent scintigraphy withindium 111 (111In)-labeled white blood cells (WBC) for the detection of a local suppuration. The procedure generally contributed to a correct diagnosis. False negative results were observed in 5 children, but in two of them positive foci were also present. The missed lesions were 2 liver abscesses, 1 lung abscess, foci of osteomyelitis and 1 pericarditis. Two cases of chronic granulomatous disease are presented in which increased leucocyte accumulation was not observed in proven instances of infection.</abstract>
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